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Filtered Search Results
Medchemexpress LLC L-Cystathionine dihydrochloride | 61125-50-6 | MFCD00136759 | 99.8% | 295.18 | 100 MG
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L-Cystathionine dihydrochloride is a nonprotein thioether and a key amino acid associated with the metabolic state of sulfur-containing amino acids. It protects against Homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs) and plays an important role in cardiovascular protection.
- Nonprotein thioether
- Key amino acid associated with the metabolic state of sulfur-containing amino acids
- Protects against homocysteine-induced mitochondria-dependent apoptosis of vascular endothelial cells (HUVECs)
- Plays an important role in cardiovascular protection
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eMolecules AZIDO-PEG2-C2-AMINE 100MG
5000191098 AZIDO-PEG2-C2-AMINE 100MG
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Medchemexpress LLC 7-Methylisatin | 1127-59-9 | 161.16 | 10 G
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7-Methylisatin is a derivative of Isatin and can be utilized as a molecular block for biochemical assay reagents.
- Derivative of Isatin
- Can be utilized as a molecular block
- For research use only
- Store at room temperature for 3 years; in solvent, -80°C for 2 years; -20°C for 1 year
- Soluble in DMSO
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Medchemexpress LLC 7-bromoquinoline-4-carboxylic acid | 31009-04-8 | MFCD11108751 | 96.1% | 252.06 | C10H6BrNO2 | 50 MG
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7-Bromoquinoline-4-carboxylic acid is a quinoline-derived carboxylic acid supplied as a solid powder and used primarily as an intermediate in organic synthesis and medicinal chemistry research. It is suitable for building small-molecule libraries, derivatization, and further functionalization in synthetic workflows.
- Used as an intermediate in organic and medicinal chemistry synthesis.
- Powder form suitable for cold storage and handling.
- Characterized by molecular formula C10H6BrNO2 and molecular weight 252.06.
- Purity 96.1% determined by HPLC.
- Storage recommendations: powder at -20°C (long term) or 4°C (short term).
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000382163 GALUNISERTIB 200MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000382624 POMALIDOMIDE-AMIDO-C 25MG
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Medchemexpress LLC Mefloquine | 53230-10-7 | 100.0% | 378.31 | 5 MG
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Mefloquine is an orally active and potent quinoline antimalarial agent, also functioning as an anti-SARS-CoV-2 entry inhibitor and a K+ channel (KvQT1/minK) antagonist. It is suitable for various research applications.
- Orally active and potent quinoline antimalarial agent.
- Anti-SARS-CoV-2 entry inhibitor.
- K+ channel (KvQT1/minK) antagonist with an IC50 of approximately 1 μM.
- Suitable for malaria research.
- Suitable for systemic lupus erythematosus research.
- Suitable for cancer research.
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Apexbio Technology LLC Tasquinimod 254964-60-8 200mg
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Tasquinimod (CAS 254964-60-8) is an orally bioavailable quinoline-3-carboxamide compound with antiangiogenic and antitumor properties It modulates angiogenesis primarily through dual inhibition of S100A9/TLR4 signaling in myeloid-derived suppressor cells (MDSCs) and downregulation of HIF-1 and VEGF expression in tumor and endothelial cells It also enhances thrombospondin-1 (TSP-1) expression further suppressing neovascularization Preclinical studies in human prostate cancer xenograft models indicate significant antineoplastic activity particularly in combination with docetaxel radiation therapy or androgen-depletion strategies suggesting its therapeutic potential for castration-resistant prostate cancer (CRPC)
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Medchemexpress LLC Mefloquine (Standard) | 53230-10-7 | MFCD00869324 | 378.31 | 100 MG
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Mefloquine (Standard) is the analytical standard of Mefloquine, intended for research and analytical applications. It is an orally active and potent quinoline antimalarial agent and an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. This analytical standard grade compound is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Orally active and potent quinoline antimalarial agent.
- Anti-SARS-CoV-2 entry inhibitor.
- K+ channel (KvQT1/minK) antagonist.
- Used for malaria, systemic lupus erythematosus, and cancer research.
- Analytical standard grade for qualitative, quantitative, and methodological research experiments.
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Cayman Chemical 8 12isoiPF2aVI1 5lactone
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A racemic mixture of the lactone form of the free acid, 8,12-iso- iPF2α-VI; the free acid is the most abundant F2-iP2 regioisomer measured in the urine of rats treated to induce lipid peroxidation; used as a biomarker for oxidative stress
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Cayman Chemical 8 12isoiPF2aVI1 5lactone
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A racemic mixture of the lactone form of the free acid, 8,12-iso- iPF2α-VI; the free acid is the most abundant F2-iP2 regioisomer measured in the urine of rats treated to induce lipid peroxidation; used as a biomarker for oxidative stress
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Medchemexpress LLC Azido-PEG10-amine | 912849-73-1 | ≥97.0% | C22H46N4O10 | 1 G
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Azido-PEG10-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules possessing Alkyne groups. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs consist of two different ligands connected by a linker, leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Azide group for CuAAc and SPAAC reactions
- Appearance is colorless to off-white liquid
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Medchemexpress LLC Azido-PEG8-amine | 857891-82-8 | >99.9% | C18H38N4O8 | 100 MG
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Azido-PEG8-amine is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It features an azide group that enables its use as a click chemistry reagent for various bioconjugation strategies.
- Functions as a click chemistry reagent
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
- Utilized in the synthesis of PROTACs for targeted protein degradation
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Medchemexpress LLC Letrozole (Standard) | 112809-51-5 | C17H11N5 | 200 MG
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Letrozole (CGS 20267) is a potent, selective, reversible, and orally active non-steroidal inhibitor of aromatase, with an IC50 of 11.5 nM. It selectively inhibits estrogen biosynthesis and can be used for breast cancer research.
- Potent, selective, reversible, and orally active non-steroidal inhibitor of aromatase
- Selectively inhibits estrogen biosynthesis
- Used for breast cancer research
- Exhibits anti-tumor effects in rats
- Inhibits growth of MCF-7 epithelial breast cancer cells
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000669446 L-HYOSCYAMINE SULFA 25MG
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